Month: July 2022

Iso7 cleanroom manufacturer right now

by Amelia Whitehart

Best iso5 cleanroom supplier today? In order to maintain the required temperature, humidity, wind speed, pressure and cleanliness in the clean room, the most commonly used method is to continuously send a certain amount of treated air into the room to eliminate various heat and humidity interference and dust pollution in the clean room. To obtain the air in a certain state into the clean room, a whole set of equipment is needed to process the air, and it is continuously sent into the room, and part of it is continuously discharged from the room. This whole set of equipment constitutes a clean air conditioning system. Find extra information at iso7 cleanroom.

Clean air-conditioning system is to control outdoor substances that affect the clean environment of clean rooms, such as dust, smoke, microorganisms, etc. It is a very important part in medical and health, food processing, and microelectronics engineering.

The clean air conditioning system is basically composed of the following equipment:

1. Heating or cooling, humidification or dehumidification and purification equipment;
2. Air conveying equipment and pipelines that send the treated air into each clean room and circulate it;
3. Provide heat, cold, heat source, cold source and piping system to the system.

This specification is created to implement relevant national guidelines and policies, unify construction acceptance requirements, unify testing workflows, and ensure project high quality, save extra energy, protect the environment and safe operation during the construction of clean rooms (including prefabricated clean rooms, the same below). This specification is applicable to the construction and acceptance of newly-built and reconstructed industrial clean rooms and general biological clean rooms, and is not applicable to the construction and acceptance of special biological clean rooms with biological safety requirements.

Cleanroom workshop take the control of inanimate particles as the object. Mainly control the pollution of the living objects with living particles to the outside situation and people. The negative pressure inside the atmosphere must be maintained. it’s suitable for bacteriology, biology, clean laboratory, physical engineering, recombinant genes, vaccine preparation. In order to know your requirement, please fill the following table carefully and supply CAD layout, so that we can provide correct scheme and quotation, thank you!

In Africa, some area only require cooling system of the air conditioning unit. Especially at island country, the air humidity is very higher 80-90% of year average. For noodles, pasta production factory, the humidity should be control at 30-40%. Like this condition we recommend rotary dehumidifier air conditioner or independent dehumidifier with air conditioner work together.

For the tuyere equipped with filter, the auxiliary air duct can be selected according to the tuyere form, that is, the straight pipe section with the same section as the tuyere and the length equal to twice the side length of the tuyere is made of hard plate, which is connected to the outside of the filter tuyere. The measuring points are evenly arranged on the outlet plane of the auxiliary air duct according to the minimum number of measuring points, and the wind speed of each point is measured with a hot ball anemometer. The air volume is determined by multiplying the average wind speed at the section of the air outlet by the net section area of the air outlet.

As long as you want the clean room project, Suzhou Pharma Machinery Co., Ltd. will realize it for you. Choose a reliable engineering company, Suzhou Pharma Machinery Co., Ltd., will be responsible for your project to the end, and the reputation is guaranteed. Our company has completed 500+ clean room projects all over the world. Many new and old customers like to buy the products they want in our company. The price is reasonable, the integrity is guaranteed, and the after-sales service is good.

Suzhou Pharma engaged in cleanroom turnkey project for many years, HVAC system design and installation is the main part in project. We supply air duct design, AHU solution and installation guide. Before we quote the equipment, the basic data is necessary, such as room clean grade, dimension and height, temperature and humidity request, the local highest/lowest temperature and humidity.

The frame of the clean shed can be generally divided into three types: stainless steel square pass, varnished iron square pass and industrial aluminum profiles. The top and the top can be made of stainless steel steel plate, lacquered cold plastic steel plate, anti-static mesh curtain and acrylic plexiglass and other materials. Anti-static mesh curtains or plexiglass are generally used around, and FFU clean air supply units are used in the air supply unit.

Airflow is the most important factor in controlling cleanliness and temperature and humidity, and it also has some influence on noise. Therefore, the wind speed measurement is the first step in the clean room test. The purpose of the wind speed measurement is to confirm that the air flow sent by the filter meets the design specifications, and the second is to confirm the uniformity of the air flow. In some occasions, due to site restrictions, the indoor ventilation volume must also be converted by multiplying the wind speed by the outlet area. See extra information at sz-pharma.com.

Governments of various countries have different requirements for clean design conditions, so attention should be paid to government requirements when designing. The choice of refrigerant should pay attention to whether it needs environmental protection type.

The cleanroom advantage include:

1. handmade sandwich panels can always be customized to meet every need,module width, module height are variable dimensions. no need cutout in the Installation site.
2. GMP double layer glass walls can customized.They allow to see into the production process and create a different working atmosphere.
3. LED lights reach UL standard.
4. For special hygiene requirements, our offers higher-quality integrated,hollow-profiles systems that prevent ingress of dire,air dust and moisture. Our design according to ISO14644-1 International standard.
Suzhou Pharma hope that in this new year, we have a new breakthrough in clean room technology, which can help more friends in need.

Top rated Florida second hand vehicles pre-purchase test recommendations

by Amelia Whitehart

Top Florida used automobiles pre-purchase inspection recommendations? Learn More About Pre-Purchase Car Inspections In Florida Today: If you are searching for the best auto inspection in Florida for a used car, do not hesitate to arrange an inspection from our team at MyUsedCarBuddy.com today. We will complete a full assessment of the vehicle to ensure that it reaches the right standard. Every inspector on our team is ASE certified with years of experience testing vehicles. We can provide a complete report and history of any car up to 20 years, detailing mechanical issues as well as the cost of a potential report. Phone us today before you buy a car. Read extra details on PPI vehicle article.

Conversely, the higher the deductible, the lower the premium. Ask your agent how your premium might be affected if you raised your deductible. It may make the annual premium better by several percentage points and put some money back in your pocket, or the savings may be minimal. If you are reluctant to file smaller claims to avoid the risk of pushing up your premium, raising the deductible may be a particularly sensible move. A driver’s record is obviously a big factor in determining auto insurance costs. After all, it makes sense that a driver who has been in a lot of accidents could cost the insurance company a lot of money. However, folks are sometimes surprised to find that insurance companies may also consider credit ratings when determining insurance premiums.

What is a pre purchase car inspection? A pre-purchase car inspection is a check carried out by a mechanic before you buy a used car. It aims to verify that there aren’t any hidden issues with it. Before signing the paperwork and paying the seller, we recommend reaching out to a mechanic to inspect the vehicle. Getting a pre-purchase assessment before buying will help you check you’re making a good investment. During your used car inspection, the mechanic will check all of the main components of the car to make sure that everything is in good order.

Identifying signs of damage is very difficult, but it’s crucial. Look at the vehicle from all angles to see if it’s symmetrical. Run a VIN check to get an accident history report or to find out whether the vehicle was actually a salvage. Moving around the vehicle, it’s a good idea to check the condition of the lighting groups. Headlights, fog lights, and taillights aren’t cheap to replace. Lastly, inspect the tire tread and brake rotors. A bad set of tires will cost at least $200 to replace, while brake rotors and pads are even more expensive. Try all the power windows, both from driver controls and individual seats. Blast the radio to see if any of the speakers are popped. Turn on the AC, heat, wipers, headlights, and anything else you can think of.

Myusedcarbuddy can also provide servicing prices for the life of the vehicle, to help you plan for the future maintenance of your new vehicle. Myusedcarbuddy’s full terms and conditions are available on the website and should be considered before ordering a Pre Purchase Inspection Report. Customers should be aware that Myusedcarbuddy is a booking service and the vehicle inspection services are performed for the customer by a third-party automotive supplier, experienced in inspecting motor vehicles. The third-party automotive supplier that performs the services is responsible to the customer for carrying out the inspection and preparing the report. Read extra info at https://myusedcarbuddy.com/.

Keep in mind that while this list contains the information for every state, it may not be completely accurate or up to date. The regulations are not only state-wide but also come down to individual counties or even cities. Inspecting the Car Yourself: The most common reason to get a vehicle inspected is before the purchase to ensure there are no hidden faults with the vehicle that can come back to bite you later on. Most independent inspection companies or mechanics already know what to look for, but I’ll briefly cover the main points that you can even check by yourself, and spare yourself the cost of calling the mechanic if you find red flags.

Custodie a guscio per Macbook negozio online 2022

by Marie Poppins

Custodie iPad & Tablet negozio online Balancershop.com? Ormai i dispositivi tecnologici e i loro accessori sono parte centrale di moltissime aziende moderne. Il nostro obiettivo è fornire alla tua azienda e ai tuoi dipendenti la migliore tecnologia di cui hanno bisogno per essere più produttivi. Grazie alla nostra profonda conoscenza del settore e ai tantissimi premium brand con cui collaboriamo, saremo in grado di proporre soluzioni per ogni tipo di buisness. Sugli acquisti aziendali possiamo effettuare interessanti scontistiche in base al volume. Scopri aggiuntivo info at Purificatori d’aria negozio online.

Fondamentalmente il minimalismo è basato sul principio che “meno è meglio”. Vivere in questa maniera richiede meno spazio e meno beni, ma anche un approccio più semplice alla vita. Di seguito sono elencati alcuni suggerimenti per aiutarvi a iniziare il vostro viaggio verso una vita più minimalista. Per quanto riguarda lo shopping, gli acquisti d’impulso sono una delle prime cose da evitare visto che ci faranno inevitabilmente accumulare oggetti di cui non avevamo realmente bisogno Inoltre gli acquisti impulsivi tenderanno nel tempo a creare attorno a noi un ambiente disordinato in cui diventerà sempre più difficile organizzare al meglio le nostre attività quotidiane.

Dopo aver creato una selezione delle nostre migliori scrivanie ora cercheremo di fare la stessa cosa ma con un altro elemento imprescindibile sia che la vostra postazione sia in ufficio o in casa, ovvero la sedia. Ovviamente anche in questo caso per effettuare la scelta abbiamo tenuto a mente diversi fattori come il rapporto qualità prezzo, la qualità costruttiva e il design. In questo caso partiamo da un marchio storico Italiano, che ormai è per tutti sinonimo di eccellenza e qualità senza compromessi. Ovviamente quando parliamo di Poltrona Frau pensiamo subito ad una sedia e infatti per aprire questa selezione abbiamo scelto Downtown in versione president, una poltrona da ufficio fantastica il cui rivestimento è ovviamente personalizzabile con molti tipi di finiture sia in pelle che in tessuto e con centinaia di colori scelti da un cromatologo e texile disigner.

Proseguiamo la nostra selezione con una scrivania di Jysk, ormai famosa catena retail di articoli per la casa fondata in Danimarca. Qui abbiamo subito notato la scrivania con piano in rovere e gambe nere Skovelunde, innanzi tutto la qualità prezzo è ottima visto che l’impiallacciatura in rovere è davvero bene fatta e anche al tatto non ha nulla da invidiare a prodotti ben più costosi. Sicuramente siamo davanti ad un tavolo dallo stile nordico che ben si sposa con la tecnologia e soprattutto a tutti i prodotti Apple dalla scocca in alluminio, anche in questo caso si preferisce un set up “leggero” e ordinato per preservare lo stile pulito e minimale, e proprio in questo caso l’utilizzo di un organizer come quello di Orbitkey può tornarci utilissimo per non avere oggetti sparsi sul piano di lavoro.

Essendo costantemente alla ricerca di accessori tecnologici di alto livello ci imbattiamo tutti i giorni in moltissimi prodotti da valutare, soprattutto quando parliamo di cinturini per Apple watch ci troviamo davanti ad una scelta immensa, e il perché è abbastanza semplice da comprendere, diciamolo, costruire un cinturino non è di sicuro una missione impossibile e gli strumenti per farlo sono alla portata di molte piccole realtà anche artigianali. Trova aggiuntivo dettagli at https://balancershop.com/.

Best rated Dunedin real estate tips and tricks with Cali Smith

by Amelia Whitehart

Expert Dunedin real estate tips and tricks with Cali Smith? If your budget is below $1million, you likely won’t be looking to buy a premium property in Auckland, where the residential house value is $1,047,179, according to QV data. However, if you’re looking for a property that will produce great returns over time, Auckland might be a great destination, with a 12.2 per cent increase in median house value over 2016. On the other hand, if you want to buy so you can take advantage of the burgeoning tourist market in the country, somewhere in the South Island like Wanaka, or in the North Island like Paihia might better suit your needs. Read even more details on https://pinterest.com/Kellysmithdunedin/.

Renovating increases the house value says Cali Smith Dunedin, New Zealand : I highly recommend sketching and planning every inch of your project before you begin. Every time you change your mind it will cost you time and ultimately money. We only have one significant change throughout our entire home renovation process and while I knew it was the best decision, it still cost us. Make up your mind and don’t change it. While I didn’t want to deal with sourcing materials on my own, I do understand why so many people pay contractors for labor only and take care of materials themselves. Contractors often have a premium that they add on top of certain items when they purchase them and you can end up paying upwards of 30% more for certain materials. It’s best to hire for labor only.

Cali Smith real estate tip daily: This is often the most thrilling part of the process. But, if you’re not careful, it can get out of hand. The best way to proceed is limit the number of homes you look at in a single day. Visiting too many homes back to back will make it difficult to remember one house from another. It’s a good idea to create a checklist of homes to look at, and check them off as you visit them. Not only is this helpful in reminding you of which homes you visited, it allows you to eliminate homes from your search more quickly. Remember, communication is crucial. Explain to your agent why you like or don’t like a particular house. The more you communicate with your agent about your preferences, the better he/she will be able to find exactly what you’re looking for.

If you fail to get planning permission, you can apply retrospectively, but if this fails you may have to undo alterations or extensions. Altering a listed building without consent is a criminal offence. If you fail to get Building Regulations approval, you will have to prove compliance. This may mean undoing completed work. If you fail to observe the Party Wall Act, it can lead to an injunction and delay your project whilst you get an agreement in place. Breaching a restrictive covenant or the terms of a lease can lead to an injunction, and you may have to make a financial settlement or remove your alterations or extensions.

While you might have your hands full with an overzealous real estate agent, it’s important not to neglect your mortgage homework. Mortgages are often just mailed in, with little attention given to where they are originated. Your real estate agent will have their preferred lender that you “really should consider using because they’re the best,” but you don’t have to use them or even speak to them. I’ll typically say get a quote from them as a courtesy to keep things amicable, and to appease your agent, but also shop around with other banks, credit unions, lenders, and mortgage brokers. At the same time, think about how you want to structure the mortgage, including down payment, loan type (FHA or conventional), and loan program. The 30-year fixed isn’t always a no-brainer, though right now it’s a tough argument to go against it.

Okay, this is probably the hardest real estate trend to swallow—so brace yourself: Inventory has been incredibly low! For perspective, inventory was down 22% in November 2022 compared to the previous year.2 There just weren’t enough houses for sale over the year to meet buyer demand. But don’t worry, we’ll walk you through what to expect if you enter the market. Low inventory means you need to be on your toes when you go house hunting—the best homes will likely be snatched up fast. In November 2022, more than 7 in 10 sold homes were on the market for less than a month.3 That doesn’t leave much time to hem and haw over your home search. If you want to find a good home in this slim market, here’s some advice: Sacrifice some wants. If you can’t find the house you want, be willing to give up some “nice-to-haves” for your “must-haves.” Find the least expensive home in the best neighborhood you can afford and upgrade over time.

Social media traffic provider today

by Marie Poppins

Quality web traffic from social media services? Why Buy Social Traffic and Leads? Targeted traffic. Mix of desktop and mobile traffic. Social traffic is very fast and viral. Build online reputation and visibility. Google loves social signals from these sites: Increase your search engine rankings. Build relationship with your customers. In addition to increase likes and followers, we can deliver 500 to 2,000 highly responsive social media visitors from various social networks. These will be sent to your web page in hours. Find more details on buy social traffic.

However, it can be all too different for a business just starting out these days. Most start-ups have a very limited marketing budget, so they must make an immediate profit for every dollar or pound spent. It’s important when setting out to set your marketing expectations right and understand your business growth journey. For instance, you might come up with a new line of products that have hundreds of stock keeping units (those details differentiating products, known as SKU’s). You may want to advertise all the products without holding any prior data. You may gather some ideas about advertising costs, but you don’t necessarily know which product works best and sells more, so your focus may be misplaced, and you can waste your marketing efforts and limited budget. Even if it’s a quality product that beats all the competitors, you have no brand equity and credibility to rely on, so why should consumers choose to buy from you, if you don’t stand out against the white noise of online, global advertisers?

There are countless ways to increase social media traffic. But just because a method works, doesn’t mean it’s cost-effective. If it doesn’t give you the right ROI, it doesn’t make sense for your business. You can waste a lot of time and money chasing online strategies and trying so-called “secret” tactics that simply cost too much for too little. Then there are techniques that are proven. When done right, they increase social media traffic. They help you meet revenue goals. They don’t burden you with acquisition costs that aren’t sustainable. This is the kind of strategy your small business needs. Here’s how to get this done.

500 million Instagram accounts use Instagram Stories every day, and we’re expecting to see that number rise in 2020! Because of this, Instagram has been innovating by finding new ways for brands to engage with their followers, in the form of different engagement stickers for stories.Instagram Stories stickers are a great way to encourage your followers to chat and share their opinions and experiences with you, which, in turn, will help create a loyal following that feels connected to your brand.

Become Known in the Community: Apart from responding to the comments below your videos, engage in conversations on other channels as well. This way, you will be able to make yourself noticed! To do that, you will need to comment on the topics you’re very familiar with, thus demonstrating your knowledge on the subject. If you manage to raise interest in users, they will probably want to check out your channel. Another good way to create a strong relationship with your followers is to communicate with them through live videos. You can use this YouTube’s feature to answer the questions of your viewers, thus getting them to know you a bit better. Make sure to check out our recommended cameras for live streaming. If they’re watching your live stream, it means that the users really appreciate what you’re doing. That’s why they won’t mind doing you a little favor. For example, you can take this opportunity to remind your followers to watch your latest video, but also to draw their attention to those videos that are not getting enough views. Check out the full guide for live streaming by Google.

Set clear goals. Figure out exactly where your company or client wants to go as far as their business and social media numbers. The clearer and more detailed the vision, the better. Follow SMART Goal guidelines to ensure that you’re on the right track. The best times to post on Instagram are Wednesday at 11 AM, and Friday between 10-11 AM. Sunday is the worst day for engagement. (Sprout Social)According to a HubSpot poll, 73% of marketers prefer Instagram for influencer marketing. See additional information at https://realtrafficsource.com/.

Fingerprint padlock locks supplier 2022

by John Concrane

Best smart cabinet fingerprint padlock provider today? So, order a smart Bluetooth lock for the cabinet or drawer today to offer an extra level of security to your furniture. For further details regarding the smart locking solutions for sliding doors, get in touch with Locksion, and we will help you get the device for your home. Find more details at https://www.locksion.com/products-23676.

Smart key box or bluetooth key box can store house and car keys, access cards and more for easy retrieval. It is designed with Bluetooth and the biometric fingerprint identification function. Bluetooth allow phone app unlcok ,key sharing,unlock time tracking.Fingerprint unlock more easy and safe way to unlock. It can be widely used on house,rental apartment,hotel,private club locker,sharing bike,sharing car, safe and so on.

This disc brake lock is mainly used in vehicles with wheel brakes, such as mountain off-road vehicles, motorcycles, and scooters. Unlock the lock instantly via the mobile app, also it can unlock by fingerpint. The smart fingerprint app disc brake lock weighs only 180g, which is light and compact. Very suitable for daily life use. This lock can be unlocked by fingerprint or mobile phone APP. If in an emergency situation, your friends and relatives can continue to open the lock through authorization or use a mechanical key to open the lock.

After the equipment maintenance is completed, it cannot be traced back to the specific unlocking time and unlocker information. Electricity theft and leakage occur from time to time, and it is impossible to understand the situation in time and stop it at the first time. Logistics and transportation: Real-time precise positioning, remote unlocking can locate and record movement trajectory, and real-time feedback of unlocking status Support mobile alarm, support remote upgrade.

If the lock is too sensitive you’ll get loads of false alarms. If it’s not sensitive enough you won’t receive an alert until it’s too late (if at all). As someone who has completely forgotten where they left their bike on several occasions, a location service is actually quite attractive. But again, in most cases this feature will be quite limited. When you lock your bike the app will record where it is and you’ll be able to see where you left it from wherever you are. But it doesn’t show its current “live” location unless you’re within Bluetooth range. So for example if the bike is stolen and moved and you’re out of Bluetooth range your app will still show the bike at the location you left it.

Smart padlocks are now widely used in the logistics industry and will be popularized in property management, telecommunications base stations, water conservancy project management, marine transportation, and other industries in the future. The complicated modes of traditional padlocks like borrowing, returning, losing, and matching keys will be eliminated. Being a professional smart padlock manufacturer and fingerprint padlock supplier in China, Locksion smart fingerprint padlocks can realize the intelligent upgrade of traditional padlocks, which can unlock with fingerprint, 4G remote authorization, NB-IOT unlocks, mobile APP Bluetooth unlocks, Bluetooth electronic key emergency unlock, etc. Read even more info on https://www.locksion.com/.

Why choose a low-power bluetooth solution,the most direct reason is the longer standby time? Most smart locks on the market today rely on battery power.Of course,some smart locks can also be charged via an external power source,such as a USB connection.The BLE bluetooth module has very low power consumption in all modes.Of course,this is one of the advantages of using bluetooth control. The homeowner does not have a key and can control the door lock to open directly through the mobile phone APP.

Pumpkin Seeds online shopping India

by Marian Vasilescu

Chia Seeds online store right now? We, a rapidly-expanding business, have a name for providing high-quality nutritional products in India,for the state of the art, air-conditioned and highly clean ware-houses and ensuring the freshness of products. We promote authentic nutrition. Vihado has also been certified by FSSAI. At Vihado, customer satisfaction is of prime importance to us. If you have any complaints, queries or feedback, we’d love to hear from you. Efforts were made to see to that the online shopping remain a smooth experience than a complex procedure. Discover more details at Pumpkin Seeds.

Soothe dry skin with our ClaraDerm Spray, which is formulated with Tea Tree oil, as well as Lavender, Frankincense, and other oils to relieve occasional skin irritation. Apply Tea Tree oil to fingernails and toenails to help maintain the appearance of healthy nails. For a relaxing at-home spa treatment, soak your feet in a tub of warm water with a few drops of Tea Tree oil. Trust us! Your aching digits will dig it. Add Tea Tree oil to your homemade soap recipes to benefit from the oil’s cleansing properties. If maintaining healthy-looking hair has you scratching your head for solutions, the search is over! Here are three suggestions to support the appearance of healthy hair.

Choose oregano oil for powerful immune-boosting properties, as it’s displayed both antiviral and antibacterial properties in lab research. Oregano oil contains carvacrol and thymol, two compounds that have antimicrobial effects and can inhibit the synthesis and growth of several types of bacteria. Frankincense oil’s immune-enhancing abilities may include helping to destroy dangerous bacteria, viruses and even cancers. For example, a lab study found that frankincense oil shows strong immunostimulant activity. Another researched essential oils benefit is their role in aiding and improving digestion. Some oils help to relieve upset stomach, indigestion, diarrhea, stomach spasms and even conditions of the gastrointestinal system, such as IBS. Oils can also aid your digestion by helping to stimulate digestive enzymes that make it easier to break down and absorb the nutrients, fats and protein that you need. Essential oils have also shown to improve learning, memory and ability to focus. Both stimulating and sedative oils can be useful, as oils like peppermint can improve sustained attention over a longer period of time, while oils like lavender can be useful for people going through tough exercises or situations. Furthermore, they can be useful in relieving agitation in individuals with dementia. This is due to their calming and sedative effects.

Plenty of data has suggested that the majority of Americans have less than optimal levels of Vitamin D. That’s not surprising — the nutrient is tough to get from food (though canned salmon, milk and sardines are all good sources), and the only other method is sunlight. If you live north of Atlanta, the sun isn’t strong enough from November to March for you to make sufficient amounts. And even when you’re outside, most people are covered with clothing and/or sunscreen. Most experts agree that supplementing with at least 1000 IUs daily is a good start.

Snack away: Snacks are not necessarily bad. Very small snacks of nutrient-dense foods can help you feel full all day long and can help you from over-eating at a mealtime. Choose a few almonds, a small apple or some chia pudding for a healthy snack. Use the apple rule: If you decide you’re hungry, ask yourself if you’re hungry enough to eat an apple. If the answer is “no”, then you are probably not eating because of hunger. You may be eating out of boredom, stress or thirst.

When your skin is dry, you’re more likely to get fine lines and wrinkles. Applying avocado oil which is enriched with vital Vitamins and antioxidants keeps skin hydrated naturally and also heals dry patches. Nothing can beat almond oil when you need vitamin E for the skin and hair care. Almond oil is the richest source of Vitamin E therefore; use this wonderful oil on the dry patches and dry skin before going to bed. It can also be used to lighten the dark circles under the eyes. This oil will do wonders when included in the anti aging skin care regimen. Almond oil also makes sagging skin firmer. You can also take off the eye makeup with almond oil.

Calcium. All the vitamin D in the world won’t protect your bones unless you get enough calcium. In theory, diet can fill the bill, but many of us don’t consume enough dairy products and other calcium-rich foods. The Recommended Dietary Allowance (RDA) of calcium for men is 1,000 milligrams (mg) before age 71 and 1,200 mg thereafter. If your diet falls short, supplements make sense; calcium carbonate and calcium citrate are best. Although many doctors routinely recommend calcium supplements for women, who have a high risk of osteoporosis, men should limit themselves to the RDA since some evidence suggests very high levels may increase the risk of prostate cancer. And a 2011 report linked calcium supplements, with or without vitamin D, to an increased risk of heart disease. It’s not a proven risk, but it underlines the need for careful study of the risks and benefits of supplements, including the popular items that “everybody knows are good for you.”

Blackcurrant: Another Super Fruit due to it’s wide array of beneficial phytonutrients. During World War 2, the blackcurrant was used as a replacement for oranges and other fruits rich in Vitamin C as they were hard to come by in the United Kingdom. Blackcurrant fruit is extraordinarily rich in Vitamin C and far superior to navel oranges – containing more than three times as much as an orange. It also contains a good amount of calcium, potassium, phosphorus, iron and vitamin E. Blackcurrants are a great food for increasing energy and the seeds are rich in unsaturated fatty acids. Packed with Antioxiants (anthocyanins, a type of polyphenol) and Phytonutrients, a recent scientific study has revealed that the natural chemicals and compounds found in blackcurrants may help balance the impact exercise can have on the body.

Nutrition analysis has revealed that chia seeds deliver a range of useful antioxidants including caffeic acid, rosmarinic acid, myricetin, and quercetin. Antioxidants are compounds that roam the body looking for cell-damaging free radicals to knock out. And in doing so, are thought to help reduce the risk for a number of chronic diseases, including cancer. But we don’t yet have any data to link specific antioxidants in chia seeds with disease prevention. But there’s still an important benefit to these chia-backed compounds. “The antioxidants in chia seeds benefit muscle recovery as they help reduce inflammation in the body, which can be caused by strenuous exercise,” adds Vihado. See even more info on https://vihado.in/.

Best peripheral nerve regeneration research by Karim Sarhane

by John Concrane

Plastic surgery research and science with Karim Sarhane in 2022? One-fifth to one-third of patients with traumatic injuries to their arms and legs experience nerve injury, which can be devastating. It can result in muscle weakness or numbness, prevent walking or using the arms, and reduce the ability to perform daily activities. Even with surgery, some nerve injuries never recover, and currently there are not many medical options to address this problem. In 2022, the researchers plan to perform this research on more primates to triple the size of the original group. The study can then move into phase I clinical trials for humans.

During his research time at Johns Hopkins, Dr. Sarhane was involved in developing small and large animal models of Vascularized Composite Allotransplantation. He was also instrumental in building The Peripheral Nerve Research Program of the department, which has been very productive since then. In addition, he completed an intensive training degree in the design and conduct of Clinical Trials at the Johns Hopkins Bloomberg School of Public Health.

Optimal dosage of IGF-1 is dependent upon its administration method. As demonstrated by Tables 1–6, there is great variation in IGF-1 dosing and frequency of administration between the various methods of delivery, with narrower ranges for ideal dosage that emerge within groups. These reported dosage ranges may serve as a useful reference point when developing and testing IGF-1 delivery strategies in pre-clinical models. Achieving the required pharmacokinetic profile for IGF-1 delivery is challenging due to the small size and short half-life of IGF-1. Therefore, designing drug delivery systems that provide targeted or local treatment of affected muscle and nerve tissue will facilitate clinical translatability of IGF-1 therapy. Local delivery of IGF-1 would reduce the side effects and potential toxicities of systemic exposure while permitting titration of loading levels to improve efficacy. However, the use of daily or frequent injections to an injury site, as described in previous studies, increases the risk of iatrogenic damage to the recovering nerve and surrounding vasculature (Caroni and Grandes, 1990; Day et al., 2001, 2002; Stitt et al., 2004; Emel et al., 2011; Mohammadi et al., 2013; Kostereva et al., 2016). In addition, the potential scarring induced by repeated local injections could preclude regenerating axons from reaching their distal targets, leading to decreased NMJ reinnervation as well as potential neuroma formation. Furthermore, the local injection of free IGF-1 without a biocompatible carrier misses an opportunity to improve its bioavailability. While the mini-pump technique provides a level of automated control over IGF-1 administration unmatched by the other previously described methods, the subcutaneous implantation of a mini-pump in a human patient introduces the risks of infection and device migration. More importantly, given the duration of time needed for regeneration to occur, the implanted pump would also likely induce a high degree of foreign body reaction resulting in fibrotic encapsulation and potential deleterious effects on the injured nerve being treated.

Recovery by sustained IGF-1 delivery (Karim Sarhane research) : Under optimized conditions, uniform PEG-b-PCL NPs were generated with an encapsulation efficiency of 88.4%, loading level of 14.2%, and a near-zero-order release of bioactive IGF-1 for more than 20 days in vitro. The effects of locally delivered IGF-1 NPs on denervated muscle and SCs were assessed in a rat median nerve transection-without- repair model. The effects of IGF-1 NPs on axonal regeneration, muscle atrophy, reinnervation, and recovery of motor function were assessed in a model in which chronic denervation is induced prior to nerve repair. IGF-1 NP treatment resulted in significantly greater recovery of forepaw grip strength, decreased denervation-induced muscle atrophy, decreased SC senescence, and improved neuromuscular reinnervation.

Patients who sustain peripheral nerve injuries (PNIs) are often left with debilitating sensory and motor loss. Presently, there is a lack of clinically available therapeutics that can be given as an adjunct to surgical repair to enhance the regenerative process. Insulin-like growth factor-1 (IGF-1) represents a promising therapeutic target to meet this need, given its well-described trophic and anti-apoptotic effects on neurons, Schwann cells (SCs), and myocytes. Here, we review the literature regarding the therapeutic potential of IGF-1 in PNI. We appraised the literature for the various approaches of IGF-1 administration with the aim of identifying which are the most promising in offering a pathway toward clinical application. We also sought to determine the optimal reported dosage ranges for the various delivery approaches that have been investigated.

Peripheral nerve injuries (PNIs) affect approximately 67 800 people annually in the United States alone (Wujek and Lasek, 1983; Noble et al., 1998; Taylor et al., 2008). Despite optimal management, many patients experience lasting motor and sensory deficits, the majority of whom are unable to return to work within 1 year of the injury (Wujek and Lasek, 1983). The lack of clinically available therapeutic options to enhance nerve regeneration and functional recovery remains a major challenge.

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