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Iris Valera Larios about blood disorder treatments : What is the incidence of ITP? In the USA about 3,000 to 4,000 of the population have ITP at any one time, and it is not more prevalent in any particular racial or ethnic group. What are the symptoms of ITP? Some people with ITP, especially those with a count over 50, may have no symptoms at all, and their ITP only noticed during a routine blood test. Even people with very low counts, can sometimes have few symptoms.
How is ITP diagnosed? ITP is usually diagnosed by a blood test showing that only the platelet count is low, and the platelets, red blood cells and white blood cells all look normal. A bone marrow biopsy may be taken at a later stage if the ITP continues, in which a small sample of bone marrow will be taken under local anaesthetic and examined under the microscope. Additional blood tests may be taken at this time to exclude rare clotting or immune diseases that can mimic ITP. If the bone marrow looks normal, with the usual or higher number of platelet parent cells (megakaryocytes) and other blood tests are normal then the doctor will diagnose chronic ITP.
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Symptoms of ITP: If the platelet count is in the range 50–100 × 109/l there is usually no bleeding or bruising. If the platelet count falls below 50 × 109/l, some bruising may occur, and below 20 ×109/l, bruising and petechiae (pinpoint blood spots under the skin) are more likely. Bleeding may occur from mucous membranes such as the nose and gums while female patients may suffer with heavy periods. The most serious bleeding tends to occur in patients with a platelet count <10 × 109/l. However, with ITP most patients with platelets less than 10 × 109/l still have no major bleeding problems.
The symptoms of ITP may look like other medical problems. Always consult your health care provider for a diagnosis. How is idiopathic thrombocytopenic purpura diagnosed? In addition to a complete medical history and physical exam, you may have these tests: Complete blood count (CBC). A measurement of size, number, and maturity of different blood cells in a specific volume of blood (to measure platelets. Additional blood and urine tests. These tests are done to measure bleeding time and detect possible infections, including a special blood test called an antiplatelet antibody test. See additional info on Iris Valera Larios.
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What are the symptoms of idiopathic thrombocytopenic purpura? Normal platelet count is in the range of 150,000 to 450,000. With ITP, the platelet count is less than 100,000. By the time significant bleeding occurs, you may have a platelet count of less than 10,000. The lower the platelet count, the greater the risk of bleeding. Because platelets help stop bleeding, the symptoms of ITP are related to increased bleeding. However, each person may experience symptoms differently.